Pepcid AC May Curb COVID-19 Symptoms – Effects Felt Within 1–2 Days

Corina Shtir and Pavel Nicoleta Craciun shared a link.
A story about Science from SciTech Daily, as featured in Newsfusion’s Science News app.
A story about Science from SciTech Daily, as featured in Newsfusion’s Science News app.

Pepcid AC May Curb COVID-19 Symptoms – Effects Felt Within 1–2 Days
“A widely available and inexpensive drug that is used to ease the symptoms of indigestion may prove a worthy contender for treating COVID-19 infection in those whose disease doesn’t require admission to hospital, suggest the findings of a small case series, published online in the journal Gut.

The effects were felt within 24 to 48 hours of taking famotidine, and a rigorous clinical trial is now warranted to see if the drug could be an effective treatment for COVID-19, say the researchers.

Famotidine (Pepcid AC) belongs to a class of drugs known as histamine-2 receptor antagonists, which reduce the amount of stomach acid produced. Famotidine can be taken in doses of 20-160 mg, up to four times a day, for the treatment of acid reflux and heartburn.

The researchers report on 10 people (6 men; 4 women) who developed COVID-19 infection, all of whom happened to have been taking famotidine during their illness.

The severity of five cardinal symptoms — cough; shortness of breath; fatigue; headache and loss of taste/smell as well as general unwellness — was measured using a version of a 4-point scale normally applied to assess the severity of cancer symptoms (ECOG PS). … Improvement was evident across all symptom categories assessed, but respiratory symptoms, such as cough and shortness of breath, improved more rapidly than systemic symptoms, such as fatigue….Our case series suggests, but does not establish, a benefit from famotidine treatment in outpatients with COVID-19,” they caution. And it’s not clear how famotidine might work: if it might incapacitate the virus in some way or alter a person’s immune response to it”



Categories: Articole de interes general

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